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Botox Alternative: Dysport and Xeomin

For the past 15 years, Botox has monopolized the “muscle relaxing” injectable arena, but two Botox alternative competitors, Dysport and Xeomin, have recently entered the market

In recent years, they were both approved for use in Canada, following FDA approval in the United States. Prior to arriving on the North American market, Dysport and Xeomin were used in Europe for years to treat neuromuscular conditions, but they are newcomers to the cosmetic industry.

Similarities with Botox, Dysport and Xeomin


There are many similarities with the three non-surgical cosmetic treatments:
Botox, Dysport, and Xeomin contain the same active ingredient, which is derived from botulinum toxin type A. Basically, it is a type of protein. All of these neuromodulators are used to relax the muscle they are injected into by blocking the signals that the nerves send to that muscle.

They need to be injected every 3 to 6 months, thus making their duration period quite similar. They all require a few days to take effect. This is called a gradual onset.

All three products are excellent for the treatment of frown lines across the forehead and the two lines that form between the eyebrows. They can also be effective for crow’s feet around the eyes, masseter reduction, and treating neck banding.

Mild side effects may be experienced by any one of them; however, Botox, Dysport, and Xeomin are all safe and effective.

The differences in these products are very minimal, there are a few that we know:


Dysport has the shortest onset period of just 1 to 2 days. Botox is 3 to 4 days, and Xeomin requires a week to see its full effect. Botox and Dysport both require refrigeration, whereas Xeomin requires none. It is assumed that Xeomin’s integrity is not compromised when injected because of this attribute.

Botox and Xeomin have the same sized molecules, which makes their unit size comparable. Dysport contains smaller molecules, so its unit size differs significantly. Basically, 50 units of Dysport equals 20 units of Botox. At this time, Dysport costs 10% less than the other two products. Botox and Xeomin are similar in price.

Patients agree that there is less stinging when injected with Dysport than Botox. Xeomin can boast that it has absolutely no additives, therefore less risk of antibody formations. Xeomin also has the least amount of protein around each active molecule, which has sometimes caused it to be less stable and spread beyond the injection site. This slight migration results in unwanted muscle relaxation.

Botox, Dysport, and Xeomin all have exceptional merit in the cosmetic surgery industry. When describing the differences, many say it is like comparing Coke and Pepsi. Some will want to try Dysport because its onset is much faster, while others who are quite satisfied with the results they’re achieving with Botox will be unwilling to switch. The three products should not be used interchangeably, and all of them should be only be injected by a certified facial plastic surgeon, plastic surgeon, or dermatologist.

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